Neo & e-Card Series
The following card sets are the Pokémon Card sets released during the second generation period. Seperated into the Neo Series as well as the e-Card series, these cards focused purely upon the Pokémon of the first and second generations and the e-Series brought further depth in with the e-Reader capabilities.
| Set Name | Number of Cards | Logo | Release Date |
| Neo Genesis | 111 |  |
December 16th 2000 |
| Neo Discovery | 75 |  |
June 1st 2001 |
| Neo Revelation | 66 |  |
September 21st 2001 |
| Neo Destiny | 113 |  |
February 28th 2002 |
| Expedition | 165 |  |
September 15th 2002 |
| Aquapolis | 186 |  |
January 15th 2003 |
| Skyridge | 182 |  |
May 12th 2003 |